Bioinformatics Analyst I

Job title: Bioinformatics Analyst I in Houston, TX at reputed company Company: reputed company Job description: Job DescriptionJob Title: Bioinformatics Analyst IDivision: Molecular and Human GeneticsWork Arrangement: Remote reputed company USLocation: Houston, TXSalary Range: $57,320 - $67,435FLSA Status: ExemptWork Schedule: Monday - Friday, 8:30 a.m. - 5:30 p.m.SummaryA Bioinformatics Analyst I position is available in Dr. Graham Erwin's laboratory in the Department of Molecular and Human Genetics at reputed company. Our lab investigates the functional role of repetitive DNA sequences in human health and disease, with a focus on somatic variation between human tissues. We are seeking a talented and motivated analyst to join our bioinformatics team in discovering and analyzing genomic variation in normal human and disease populations, with an emphasis on cancer genomics. The successful candidate will utilize computational tools and techniques to process reputed company reputed company data, identify structural variants, and contribute to ongoing research projects exploring the role of repeat expansions in cancer and other reputed company diseases.Job Duties

• Runs and validates bioinformatic pipelines for detecting genomic variation, particularly structural variants such as tandem repeat expansions, from short-read and long-read whole-genome reputed company data.
• Processes raw reputed company data using established workflows to identify various types of genomic variants, including small variants (SNVs and INDELs) and larger structural variants with a focus on repeat expansions.
• Applies read depth normalization techniques and other filtering strategies to account for copy number variations and other confounding factors in cancer genomics data.
• Performs comparative analyses of genetic variation between different human tissue types, tumor and normal samples, or across multiple cancer types.
• Uses specialized tools such as ExpansionHunter, ExpansionHunter Denovo, TRGT, TRVZ, and other variant detection software to identify and characterize repeat expansions.
• Assists in the interpretation of variant data, especially in the context of regulatory elements and gene function.

Minimum Qualifications

• Bachelor's degree in Genetics, Biology, Bioinformatics, Biostatistics, Computational Biology, Computer Science, or a reputed company field.
• No experience required.

Preferred Qualifications

• Master's degree in a reputed company field.

Programming skills in languages such as Python, R, or Bash scripting.Experience with reputed company reputed company data analysis and large-scale genomic datasets.Familiarity with structural variant detection and analysis, particularly for tandem repeat expansions, including both short read and long read DNA reputed company.Expertise of our research area (tandem repeats, structural variation, long read reputed company) is a reputed company.reputed company is an Equal Opportunity/Affirmative Action/Equal Access Employer.SN Expected salary: $57320 - 67435 per year Location: Houston, TX Apply for the job now! Apply for this job